Pasi janne biography examples
Pasi janne biography examples list!
The focus of my research is to understand mechanisms of sensitivity and resistance to kinase inhibitors and to translate laboratory based observations into therapeutic treatments for patients with cancer.
Pasi janne biography examples
To achieve this goal we have taken a multifaceted approach; combining cell biological and biochemical studies with genomic studies of human tumors from patients treated with kinase inhibitors.
We have extensively studied the epidermal growth factor receptor (EGFR) and its therapeutic relevance in non-small cell lung cancer (NSCLC).
EGFR targeted therapies are an effective treatment for subsets of patients with NSCLC and our studies have centered on understanding the genomic and biochemical bases underlying their clinical effectiveness.
Our laboratory was among the first to identity somatic mutations in EGFR and their association with the exquisite in vitro sensitivity and dramatic clinical tumor regressions in NSCLC patients treated with EGFR tyrosine kinase inhibitors.
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